Northwestern University

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Filtering by: Creator Biggs, Ronald Joseph Keyword Chromosomes Keyword SMC Complexes

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Micromechanical studies on chromosomes reveal interplay between chromatin, SMC complexes, protein networks and mitotic, meiotic, and centromeric stiffness

Description:

The purpose of my thesis research has been to understand the formation of mitotic chromosome structure by using chromosome micromanipulation. Folding mitotic chromosomes from their loose interphase form into their individualized, compacted form is required for easy handling of the chromosomes for cell division. This process is facilitated by several...

Keyword:

Mitosis, Histone PTMs, Chromosomes, SMC Complexes, Biophysics, and Meiosis

Subject:

Molecular biology and Biophysics

Creator:

Biggs, Ronald Joseph

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/02/2022

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15852 and etdadmin_upload_862016