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Filtering by: Creator Brue, Christopher Robert Type Work Keyword Coordination Complexes Keyword Intrinsically Disordered Proteins Keyword Molecular Dynamics

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1. Cobalt (III) Schiff-base Complexes as Inhibitors of Pathogenic Metalloproteins

Description:: Cobalt(III) Schiff-base complexes (Co(III)-sb) have been utilized in the literature as antibacterial, antiviral, and inhibitory agents. Recent work has utilized their ability to displace endogenous metals from metalloproteins that exhibit aberrant gain of function pathologies in human disease. Specifically, in this dissertation Co(III)-sb has been applied as inhibitors of pathogenic...
Keyword:: Transcription Factors, Coordination Complexes, Cobalt, Amyloid-beta, Molecular Dynamics, and Intrinsically Disordered Proteins
Subject:: Chemistry, Biochemistry, and Biophysics
Creator:: Brue, Christopher Robert
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/02/2022
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15862 and etdadmin_upload_863221

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1. Cobalt (III) Schiff-base Complexes as Inhibitors of Pathogenic Metalloproteins