Northwestern University

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Filtering by: Creator Holmes, Austin Gable Type Work

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Molecular Mechanisms of MYCi975 and MYC target gene dysregulation

Description:

MYC regulates multiple gene programs, raising questions about the potential selectivity and downstream transcriptional consequences of MYC inhibitors as cancer therapeutics. MYC func-tions to either globally amplify RNA production or selectively regulates genes by repression or ac-tivation. In models of MYC inhibition by small molecules the functionality of MYC is...

Subject:

Molecular biology and Biochemistry

Creator:

Holmes, Austin Gable

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_904142 and http://dissertations.umi.com/northwestern:16111