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Filtering by: Creator Shapiro, Jason Solomon Resource type Dissertation Subject Cellular biology

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Description:: Iron is an essential nutrient and is critical for cellular growth and metabolism. Here, we delineate a novel mechanism by which iron alters amino acid homeostasis and mTOR activity by remodeling the cellular epigenetic landscape. We find that iron deficiency inactivates Jumonji-C domain containing histone-demethylases, resulting in histone hyper-methylation and...
Keyword:: Iron, Epigenetics, Mitophagy, Metabolism, and mTOR
Subject:: Cellular biology
Creator:: Shapiro, Jason Solomon
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2018-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15209 and etdadmin_upload_759499

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