Northwestern University

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Filtering by: Creator Wang, Juan Resource type Dissertation

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3D genome architecture and structure variations in transcriptional regulation in cancer

Description:

Cancer is a complex and heterogeneous disease characterized by aberrant gene regulation. Gene regulation is fundamentally orchestrated by the 3D genome organization which involves chromatin looping, compartmentalization, and the formation of topologically associating domains (TADs). Structural variations (SVs), such as genomic rearrangements, deletions, inversions, and duplications, are commonly observed in...

Subject:

Bioinformatics and Biology

Creator:

Wang, Juan

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

08/23/2023

Date Created:

2023-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16734 and etdadmin_upload_1013045