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Filtering by: Creator Zarate, Oscar Alberto Keyword CRISPR efficiency Keyword sgRNA design Resource type Dissertation

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1. Prediction of CRISPR-Cas9 Cleavage Efficiency Through Markov Feature Engineering and Boosting-Based Transfer Learning

Description:: In the short amount of time that genetic manipulation has been possible through CRISPR technology, myriad applications have been developed. Results from one of the most promising applications of this technology, pooled screens, have shown that single guide RNAs (sgRNAs), RNA sequences used to target specific regions of the genome,...
Keyword:: sgRNA design, CRISPR efficiency, and Machine learning
Subject:: Biostatistics, Statistics, and Bioinformatics
Creator:: Zarate, Oscar Alberto
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15353 and etdadmin_upload_773909