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Tradeoffs Between Reproduction and Aging in the Human Epigenome

Description:

Evolutionary theory predicts that reproduction entails energetic costs that detract from somatic maintenance, accelerating biological aging. In women, such ‘costs of reproduction’ (CoR) are thought to arise predominantly during pregnancy and lactation, while in men the physiological effects of the steroid hormone testosterone (T) are believed to be a major...

Keyword:

Epigenetic clocks, Tradeoffs, Disposable soma theory, Costs of reproduction, Aging, and DNA methylation

Subject:

Genetics, Evolution & development, and Biology

Creator:

Ryan, Calen Patrick

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_780539 and http://dissertations.umi.com/northwestern:15395