Index Catalog // Arch : Northwestern University Institutional Repository

Advancing Understanding of Diversity and Antimicrobial Resistance in Indoor Microbiomes

Description:: The importance of understanding indoor microbial exposure is increasingly recognized, particularly concerning the emergence of pathogens and antimicrobial resistance. With the advancements of sequencing technologies, our capability of exploring indoor microbial communities has dramatically increased. However, huge challenges remain to translate sequence-based knowledge to actionable interpretations to support human health...
Keyword:: Reference deduplication, Antimicrobial resistance, Hospital environment, Infection prevention, Microbiome, and Built environment
Subject:: Environmental science, Microbiology, and Environmental health
Creator:: Shen, Jiaxian
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 05/31/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_962596 and http://dissertations.umi.com/northwestern:16420

Advancing Understanding of Diversity and Antimicrobial Resistance in Indoor Microbiomes

Description:: The importance of understanding indoor microbial exposure is increasingly recognized, particularly concerning the emergence of pathogens and antimicrobial resistance. With the advancements of sequencing technologies, our capability of exploring indoor microbial communities has dramatically increased. However, huge challenges remain to translate sequence-based knowledge to actionable interpretations to support human health...
Keyword:: Reference deduplication, Antimicrobial resistance, Hospital environment, Built environment, Microbiome, and Infection prevention
Subject:: Environmental science, Microbiology, and Environmental health
Creator:: Shen, Jiaxian
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 03/24/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_962596 and http://dissertations.umi.com/northwestern:16420

An improved workflow for accurate and robust healthcare environmental surveillance using metagenomics

Description:: Cite this article: Shen, J., McFarland, A.G., Blaustein, R.A. et al. An improved workflow for accurate and robust healthcare environmental surveillance using metagenomics. Microbiome 10, 206 (2022). https://doi.org/10.1186/s40168-022-01412-x and Background: Effective surveillance of microbial communities in the healthcare environment is increasingly important in infection prevention. Metagenomics-based techniques are promising due to their untargeted nature but are currently challenged by several limitations: (1) they are not powerful enough to extract valid signals out of the background noise for low-biomass samples,...
Keyword:: Quantification, Quantitative metagenomics, Low biomass, Viability, Machine learning, Environmental surveillance, Sequencing depth prediction, and Infection prevention
Subject:: Metagenomics, Quantitative research, Nosocomial infections--Prevention, Machine learning, and Environmental monitoring
Creator:: K. Allison Perry-Dow, Jiaxian Shen, Vincent B. Young, Ryan A. Blaustein, Mary K. Hayden, Alexander G. McFarland, Anahid A. Moghadam, Laura J. Rose, and Erica M. Hartmann
Contributor:: Centers for Disease Control and Prevention (funding agency)
Owner:: Jiaxian SHEN
Publisher:: Microbiome
Language:: English
Date Uploaded:: 12/19/2022
Date Modified:: 12/19/2022
Date Created:: 2022-12-02
Resource Type:: Research Paper
Alternate Identifier:: DOI 10.1186/s40168-022-01412-x, PMCID PMC9716758, and PMID 36457108

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Advancing Understanding of Diversity and Antimicrobial Resistance in Indoor Microbiomes

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An improved workflow for accurate and robust healthcare environmental surveillance using metagenomics

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