Phylogenetic analysis of HIV is a useful tool in determining factors that may contribute to transmission cluster growth. To better target HIV prevention, it is necessary to understand how research and surveillance data can be combined in a meaningful way.HIV genetic sequences were collected in the RADAR cohort of YMSM...
Chapter 1 investigates asks the question how do financial frictions affect the type of human capital investments that students make in college? To study this question, I build a novel dataset covering more than 700,000 U.S. students, merging commencement records with address histories, credit bureau records, and professional resumes. I...
The Gram-negative Stenotrophomonas maltophilia is naturally found in water, soil and the plant rhizosphere, and is increasingly recognized as an important opportunistic and nosocomial infection. Despite its rising prevalence and drug resistance, there is little known about S. maltophilia pathogenesis. In this dissertation, I explored two aspects of S. maltophilia...
Prostate cancer (PCa) is the second most common cancer in American men and has led to approximately 29K deaths in 2018. The androgen signaling pathway plays a pivotal role in the pathogenesis of PCa, and androgen deprivation therapy (ADT) has been the main therapeutic approach for PCa. However, almost all...
The aviation industry is set to see another significant leap in new technology, namely electric aircraft. As of the time of this research, both 9-seat and 19-seat aircraft would be ready to be launched by air service providers under the Essential Air Service (EAS) program. While electric aircraft manufacturers are...
Lack of access to safe drinking water is a global problem, and methods to reliably and easily detect contaminants could be transformative. We report the development of a cell-free in vitro transcription system that uses RNA Output Sensors Activated by Ligand Induction (ROSALIND) to detect contaminants in water. A combination...
Within the world of art music, composers have employed a variety of techniques to infuse popular music elements into their writing. This document is an examination of specific instances of this trend in twenty-first century wind ensemble repertoire. The study is limited to twenty-first century wind ensemble works by living...
The 2005 NHL Lockout instituted a hard salary cap, which is the most limiting salary cap of the major US sports leagues. The NHL as a result doesn’t have the luxury of overpaying or dumping a contract as other professional sports leagues have, which places a huge constraint and emphasis...
This study is in consideration of the spread of COVID-19, the related various government responses, and how these responses and other demographic variables affected the spread and severity of the virus on a domestic (United States) and international level. During the last few months, the virus has spread from its...