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Sensing and Delivery of Biomolecules with Spherical Nucleic Acid Nanoparticle Conjugates

Description:

Over the past fifty years, techniques for synthesizing and manipulating matter on the 1-100 nanometer scale have led to the development of nanoparticle-based approaches to both disease diagnosis and treatment. The modification of nanoparticles with biological macromolecules such as proteins and nucleic acids has led to the development of highly...

Keyword:

Spherical Nucleic Acid, Anthrax, Aptamer, NanoFlare, Gold Nanoparticle, and CRISPR

Subject:

Nanotechnology, Bioengineering, and Biology

Creator:

Larkin, Isaac Nathaniel

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15186 and etdadmin_upload_754966
DNA Aptamer-Peptide Amphiphile Nanomaterials for Enhanced Protein Binding, Tunable Delivery, and Dynamic Signaling

Description:

Biomaterials have immense potential for studying fundamental biological processes and developing therapies to help regenerate or replace the structure and function of injured tissues. In order to accomplish this, they need to be designed to mimic the structure and function of Nature’s most important material, the extracellular matrix (ECM) surrounding...

Keyword:

Peptide Amphiphile, Growth Factor, Aptamer, Biomaterials, Self-assembly, and Extracellular Matrix

Subject:

Materials Science

Creator:

Serrano, Christopher

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_681720 and http://dissertations.umi.com/northwestern:14779

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Sensing and Delivery of Biomolecules with Spherical Nucleic Acid Nanoparticle Conjugates

DNA Aptamer-Peptide Amphiphile Nanomaterials for Enhanced Protein Binding, Tunable Delivery, and Dynamic Signaling

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