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High-Throughput Protein-Protein Interaction Screening Using Cell-Free Protein Synthesis

Description:

Protein-protein interactions are ubiquitous in living systems, and mediate important cellular processes from decision making to immunity against pathogens. Furthermore, protein-protein interactions are key to many protein therapeutics, pathogen diagnostics, and numerous synthetic biology applications. As a result, there has been significant effort to develop methods to express potential protein...

Keyword:

Minibinder, Antibodies, Diagnostics, Protein Protein Interactions, High-Throughput Screening, and Cell-Free Protein Synthesis

Subject:

Bioengineering and Chemical engineering

Creator:

hunt, Andrew

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

09/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_911343 and http://dissertations.umi.com/northwestern:16125
Uncovering the Mechanism of Intrinsic Transcription Termination in Order to Develop Point-of- Care Diagnostics.

Description:

Regulatory RNAs are found throughout nature controlling critical cellular processes and enabling cells to sense and respond to their environment. In order to provide genetic regulation, these RNAs can selectively bind to target molecules, proteins, and invading pathogens, all while modulating gene expression on both the transcriptional and translational level....

Keyword:

Synthetic Biology, Regulatory RNA , Diagnostics, Transcription Regulation, and Intrinsic Termination

Subject:

Molecular biology

Creator:

Verosloff, Matthew Stuart

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/28/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15425 and etdadmin_upload_782101

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High-Throughput Protein-Protein Interaction Screening Using Cell-Free Protein Synthesis

Uncovering the Mechanism of Intrinsic Transcription Termination in Order to Develop Point-of- Care Diagnostics.

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