Northwestern University

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Filtering by: Keyword Epilepsy Keyword Interneurons

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The Role of Mental Disorder Susceptibility Molecule CNTNAP2 in Interneuron Function and Pathology

Description:

Contactin associated protein like 2 (CNTNAP2) has emerged as a prominent susceptibility gene implicated in multiple complex neurodevelopmental disorders, including autism spectrum disorders (ASD), intellectual disability (ID), and schizophrenia (SCZ). The presence of seizure comorbidity in many of these cases, as well as inhibitory neuron dysfunction in Cntnap2 knockout (KO)...

Keyword:

Epilepsy, Dendrites, Autism, CASK, CNTNAP2, and Interneurons

Subject:

Physiology, Molecular biology, and Neurosciences

Creator:

Gao, Ruoqi

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2018-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14243 and etdadmin_upload_595693