The embryonic neural crest is a unique vertebrate stem cell population that has the ability to retain its stem attributes while neighboring cells in the embryo undergo lineage restriction. These cells possess multi-germ layer developmental potential and can give rise to a diverse array of derivatives such as components of...
Fungi have an immense untapped store of natural products, small molecules that can often be repurposed as pharmaceuticals. The genes that encode secondary metabolic machinery are often genomically co-localized into biosynthetic gene clusters. Because of the immense energetic costs that goes into producing the biosynthetic pathway and its products, strict...