Index Catalog // Arch : Northwestern University Institutional Repository

Start Over

Filtering by: Keyword Hexokinase Resource type Dissertation

1 - 2 of 2

List Gallery Masonry Slideshow

HEXOKINASE 1 SUBCELLULAR LOCALIZATION REGULATES THE METABOLIC FATE OF GLUCOSE

Description:

The product of hexokinase (HK) enzymes, glucose-6-phosphate, can be metabolized through glycolysis or directed to alternative pathways, such as the pentose phosphate pathway (PPP) to generate anabolic intermediates. HK1 contains an N-terminal domain that permits mitochondrial binding, but its physiologic significance remains unclear. We generated mice lacking the HK1 mitochondrial-binding...

Keyword:

Inflammation, Hexokinase, Macrophage, Subcellular localization, Metabolism, and Mitochondria

Subject:

Biology

Creator:

De Jesus, Adam

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_773389 and http://dissertations.umi.com/northwestern:15348
Characterization of HKDC1 and Involvement in NAFLD Development

Description:

The literature has established glucokinase (GCK) to be the principal hexokinase (HK) in the liver, operating as a glucose sensor to regulate glucose metabolism and lipid homeostasis. We have recently proposed Hexokinase Domain Containing-1 (HKDC1) to be a novel 5th HK with expression in the liver. Here, we reveal HKDC1...

Keyword:

Hexokinase, NAFLD, Liver Metabolism, and HKDC1

Subject:

Molecular biology, Biology, and Biochemistry

Creator:

Pusec, Carolina

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2018-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14450 and etdadmin_upload_626205

LIBRARIES | ARCH

Limit your search

Type

Resource type

Creator

Keyword

Subject

Language

HEXOKINASE 1 SUBCELLULAR LOCALIZATION REGULATES THE METABOLIC FATE OF GLUCOSE

Characterization of HKDC1 and Involvement in NAFLD Development

Limit your search

Search Constraints

Search Results