Northwestern University

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Filtering by: Keyword IDH1 Subject Molecular biology

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Defining and Therapeutically Targeting IDH1-WT Oncogenicity in GBM

Description:

Glioblastoma multiforme (GBM) is the most prevalent primary central nervous system tumor, characterized by resistance to therapeutic intervention, inevitable recurrence, and ultimately patient death. The dismal prognosis is due in part to underlying molecular factors that promote an intratumoral cellular state heterogeneity and protect tumor cells from cell death pathways....

Keyword:

Ferroptosis, Glioblastoma, Cancer, Stemness, Metabolism, and IDH1

Subject:

Molecular biology, Medicine, and Neurosciences

Creator:

Murnan, Kevin Michael

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15885 and etdadmin_upload_865864