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Description:: Genetic studies have found variants in the protein-degrading autophagy-lysosomal pathway (ALP) to be among the most common risk factors for developing Parkinson’s disease (PD). Macroautophagy (MA) is the arm of this pathway which delivers cytosolic components to lysosomes for degradation and is essential for neuronal health. The defining pathological protein...
Keyword:: ykt6, synuclein, Parkinson disease, SNARE, autophagy, and farnesyltransferase inhibitor
Subject:: Molecular biology, Biochemistry, and Neurosciences
Creator:: Pitcairn, Caleb
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 05/31/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:16447 and etdadmin_upload_970290

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