Northwestern University

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Uncovering modifiers of cardiomyopathy in the noncoding genome

Description:

Heart failure due to genetic cardiomyopathy is associated with a range of phenotypic expression. The studies in this body of work interrogated the role of noncoding variation in modifying cardiomyopathy phenotypes. We used cap analysis of gene expression in heathy and failed left ventricles to define the regulatory environment of...

Keyword:

noncoding, genetics, MYH7, heart failure, modifier, and enhancer

Subject:

Molecular biology, Genetics, and Biochemistry

Creator:

Gacita, Anthony Martin

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_756135 and http://dissertations.umi.com/northwestern:15193