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Data-Driven Strategies for Optimization of Human Megakaryocyte Differentiation

Description:

Platelets are circulating anucleate discs derived from megakaryocytes, and play major roles in hemostasis, inflammation, thrombosis, and vascular biology. Multi-phase culture systems for inducing in vitro platelet production from mature megakaryocytes have been explored to allow progenitor expansion, megakaryocyte maturation, and promotion of platelet formation and shedding. In this thesis,...

Keyword:

gaussian mixture models, stem cell differentiation, machine learning, and megakaryocyte

Subject:

Bioengineering, Bioinformatics, and Biology

Creator:

WU, JIA JIE

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_640286 and http://dissertations.umi.com/northwestern:14541