Northwestern University

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Natural Genetic Variation Underlies Chemotherapeutic Drug Responses in Caenorhabditis elegans

Description:

Individuals within a species vary in complex phenotypes, such as responses to toxins. This drug-response variation causes patients who are treated with the same medicine to experience a range of side effects, ultimately decreasing the efficacy of some drugs. Particular genetic variants among individuals might contribute to differential drug responses,...

Keyword:

genetics, bleomycin, linkage mapping, natural variation, drug response, and C. elegans

Subject:

Biology

Creator:

Brady, Shannon Colleen

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14708 and etdadmin_upload_667842