Northwestern University

Parent Unit Name

Login

LIBRARIES | ARCH

Menu Search

Start Over

Filtering by: Keyword iPSC Resource type Dissertation

1 entry found

List Gallery Masonry Slideshow

Misregulation of Mitochondria-Lysosome Contact Sites in GBA-linked Parkinson’s Disease

Description:

Mitochondria-lysosome contacts are recently identified sites for mediating crosstalk between both organelles, but their role in normal and diseased human neurons remains unknown. We used super-resolution and live-cell microscopy in human iPSC-derived neurons to demonstrate that mitochondria-lysosome contacts can dynamically form in the soma, axons, and dendrites of human neurons,...

Keyword:

iPSC, Interorganelle contacts, GBA, Lysosome, Mitochondria, and Parkinson's disease

Subject:

Molecular biology, Cellular biology, and Neurosciences

Creator:

Kim, Soojin

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

10/07/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_825288 and http://dissertations.umi.com/northwestern:15606