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Structural Studies of Particulate Methane Monooxygenase in a Native Lipid Bilayer

Description:

Methanotrophs, bacteria that can metabolize methane, remain a promising solution to mitigating the effects of climate change by removing atmospheric methane and converting it to useful chemical precursors. However, a full understanding of the main enzyme they use to oxidize methane, particulate methane monooxygenase (pMMO), is critical for harnessing their...

Keyword:

cryogenic electron tomography, particulate methane monooxygenase, membrane protein, cryogenic electron microscopy, and cell-free protein synthesis

Subject:

Molecular biology, Biochemistry, and Biophysics

Creator:

Koo, Christopher Wellington

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_897671 and http://dissertations.umi.com/northwestern:16003
Probing the molecular details of particulate methane monooxygenase in micelles to cells

Description:

Harnessing the metabolic potential of methanotrophic bacteria is a compelling strategy for the bioremediation of environmentally harmful methane gas. Methanotrophs can activate a 105 kcal/mol C-H bond in methane at ambient conditions using metalloenzymes called methane monooxygenases (MMOs). Particulate methane monooxygenase (pMMO) is a copper-dependent, membrane-bound enzyme that is the...

Keyword:

copper, methane, methanotroph, metalloenzyme, particulate methane monooxygenase, and membrane protein

Subject:

Microbiology, Chemistry, and Biochemistry

Creator:

Ro, Soo Yeon

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14705 and etdadmin_upload_667719

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Structural Studies of Particulate Methane Monooxygenase in a Native Lipid Bilayer

Probing the molecular details of particulate methane monooxygenase in micelles to cells

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