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Description:: Current biomaterials-based methods for in vitro ovarian follicle culture enable individual follicles or follicle classes to survive and carry out basic functions of the ovary, including hormone and release of mature oocytes upon gonadotropin stimulation. However, these current strategies do not support the survival and maturation of isolated primordial and...
Keyword:: 3D bioprinting, follicle, ovary, tissue engineering, extracellular matrix, and ultrasound
Subject:: Biology
Creator:: Gargus, Emma S
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15147 and etdadmin_upload_744725

Description:: The actions of luteinizing hormone (LH) to induce ovulation and luteinization of preovulatory follicles are mediated principally by activation of cAMP-dependent protein kinase (PKA) in granulosa cells. PKA activity is targeted to specific cellular locations by A-kinase anchoring proteins (AKAPs). I previously showed that follicle-stimulating hormone (FSH) induces expression of...
Keyword:: cyloskeleton, MAP2, vimentin, ovary, granulosa cell, and luteinizing hormone
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Maxfield Patrick Flynn
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/03/2018
Date Modified:: 10/03/2018
Date Created:: 2008-08-11
Resource Type:: Dissertation

Description:: Improving cancer treatments are saving the lives of many young women, however these treatments often lead to premature infertility. The in vitro development of ovarian follicles would provide reproductive options to these women by supporting immature follicle growth following ovarian tissue cryobanking. In addition, the system provides a platform to...
Keyword:: follicle, fertility, alginate, ovary, tissue engineering, and in vitro follicle culture
Subject:: Chemical and Biological Engineering
Creator:: Erin Rochelle West
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/19/2018
Date Modified:: 09/19/2018
Date Created:: 2008-06-19
Resource Type:: Dissertation

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