Northwestern University

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Functional organization of promyelocytic leukemia bodies during proteotoxic stress

Description:

Promyelocytic leukemia (PML) nuclear bodies act as quality control centers in the nucleus, participating in a plethora of nuclear functions. As such, PML bodies are a signature model for functional nuclear organization. PML bodies have a dynamic protein composition that responds to changing conditions of the cell. Many of the...

Keyword:

nuclear organization, no-go decay, mRNA surveillence, PML, Ataxin-1, and stress

Subject:

Molecular biology and Cellular biology

Creator:

Fanslow, Danielle

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2018-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_614059 and http://dissertations.umi.com/northwestern:14390