Inflammasomes are signaling complexes that link the recognition of pathogen and danger associated molecular patterns (PAMPs and DAMPs) by cytosolic pattern-recognition receptors (PPRs) to the activation of Caspase-1, leading to the release of the pro-inflammatory cytokines interleukin (IL)-1 and IL-18, and the induction of pyroptosis. In addition to the canonical...
Exposure to violence, which includes child abuse, neglect, witnessing domestic or community violence, crime, and sexual assault, is a national concern. Over the course of a year, 68% of children under age 17 are exposed to at least one form of violence (Finkelhor, Turner, Shattuck, & Hamby, 2015). Young children...
Very few studies have examined school racial climate in racially diverse school contexts. School racial climate refers to “perceptions of interracial interactions and the socialization around race and culture in a school” (Byrd, 2017, p. 700). The association between interracial peer interactions, psychological well-being, and academic outcomes is well documented,...
Very few studies have examined school racial climate in racially diverse school contexts. School racial climate refers to “perceptions of interracial interactions and the socialization around race and culture in a school” (Byrd, 2017, p. 700). The association between interracial peer interactions, psychological well-being, and academic outcomes is well documented,...
Recent developments in research concerning organic photovoltaics (OPVs) have overseen massive increases in device performance and the ascension of electron acceptor materials that outclass the preeminent acceptor compounds, buckminsterfullerene (C60) derivatives. New design strategies in the molecular structure of perylenediimides (PDIs) and fused-ring electron acceptors (FREAs) have increased single-junction photovoltaic...
In recent years, the social sciences have been ensnared in a crisis in which many research findings cannot be replicated (Ioannidis, 2005; Open Science Collaboration, 2015; Camerer et al., 2016; Makel & Plucker, 2014). This crisis has been attributed to a variety of problems including lack of transparency about research...
The dissertation builds on my current research to demonstrate the connection between affect and learning through machine learning and qualitative analysis of interactions where players use a complex systems game. The project is threefold: First, I developed a thinking and learning intervention, the agent-based modeling simulation Ant Adaptation. I showed...
Integrating the selective reconstruction of the past with an imagined future, narrative identity is a person’s internalized and evolving story of the self, functioning to provide life with some degree of meaning, purpose, and temporal coherence (McAdams & McLean, 2013). Moreover, narrative identity has been found to be associated with...
This dissertation addresses three distinct topics in development economics. The first chapter assesses the role of entry and exit in the measurement of misallocation in India. In the last decade, misallocation of productive inputs across firms has been proposed as a primary driver of differences in aggregate productivity over time...
Animals must establish the correct form during development. Regeneration is a process by which some animals reestablish their form following injury. This process requires both the generation of new missing cells after injury, and information to pattern new cells to reestablish the correct form. Planarian flatworms have an almost unlimited...