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LY6K Promotes Glioblastoma Tumorigenicity via CAV-1-Mediated ERK1/2 Signaling Enhancement

Description:

Background: Glioblastoma (GBM) tumors are the most malignant brain cancers and are characterized as Grade IV astrocytomas by the World Health Organization. GBM tumors can be classified into three molecular subtypes known as proneural, classical, and mesenchymal. In addition, GBM tumors also have a small population of cells known as...

Keyword:

LY6K, Methylation, Glioblastoma, ERK1/2, and CAV-1

Subject:

Molecular biology, Oncology, and Neurosciences

Creator:

Sastry, Namratha G

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

01/21/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_733180 and http://dissertations.umi.com/northwestern:15049
Human CD99L2 Regulates Leukocyte Transmigration at a Unique Step between those Regulated by PECAM-1 and CD99

Description:

CD99-Like 2 (CD99L2) is a 52 kDa type I glycoprotein expressed on leukocytes and endothelial cells as well as other cell types in mice. It is related to CD99, although it shows only 32% sequence identity. CD99L2 has been shown to play a role in leukocyte extravasation in mice under...

Keyword:

Inflammation, Transmigration, Leukocyte, PECAM, Endothelial Cell, and CD99-like 2

Subject:

Pathology, Molecular biology, and Immunology

Creator:

Rutledge, Nakisha S

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_903372 and http://dissertations.umi.com/northwestern:16098

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LY6K Promotes Glioblastoma Tumorigenicity via CAV-1-Mediated ERK1/2 Signaling Enhancement

Human CD99L2 Regulates Leukocyte Transmigration at a Unique Step between those Regulated by PECAM-1 and CD99

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