Cardiovascular disease is a leading cause of morbidity and mortality worldwide. While many therapies have been used to treat vascular disease symptomatically, gene therapy offers a means of treating the molecular dysfunctions driving disease pathogenesis. Unfortunately, gene therapy has achieved only modest therapeutic success in clinical trials due to a...
We all—users, businesses, governments, and the general public—expect internet platform companies, like Meta, Alphabet, and Amazon to govern their users. Without platform governance, we all experience disasters like foreign election interference, vaccine misinformation, counterfeiting, and even genocide.
Unfortunately, the platform companies have failed. To this day, despite the lessons from...
Peptide Amphiphile (PA) molecules developed in the author's laboratory and others have shown great versatility in creating self-assembled nanostructures with built-in biological and/or chemical functionalities. Their applications in spinal cord injury repair, angiogenesis, promoting cell adhesion and templating inorganic materials have also been well studied. Complementing previous compositional studies, where...
PRC is a PGC-1 coactivator family member responsive to serum growth factors and up regulated in proliferating cells. Unlike PGC-1α and PGC-1β, PRC has not been studied extensively and and its function or regulation remains largely unknown. Both PGC-1α and PGC-1β have been shown to be important regulators of mitochondrial...
<span style="font-family: Calibri;">BaNa-Y is a catalyst for reduction of nitrogen oxides (NO and NO<sub>2</sub>) with added reductants at temperatures of ~200 °C. Studies were performed over BaNa-Y and related catalysts to unravel the roles that nitrates and nitrites play in determining the processes and pathways involved in NOx reduction. <o:p></o:p></span></p>...
An integral transform which reproduces a transformable input function after a finite number $N$ of successive applications is known as a {\it cyclic} transform. Of course, such a transform will reproduce an arbitrary transformable input after $N$ applications, but it also admits eigenfunction inputs which will be reproduced after a...
Modern-day middle school science textbooks are heavily populated with colorful images, technical diagrams, and other forms of visual representations. These representations are commonly perceived by educators to be useful aids to support student learning of unfamiliar scientific ideas. However, as the number of representations in science textbooks has seemingly increased...