This dissertation demonstrates how related initiatives to reform narcotics laws and protect consumers from dangerous medicines – taking hold in the 1950s and institutionalized in the mid-1960s – created the foundation for a massive expansion of federal policing of illicit drugs. Centered on the history of the Food and Drug...
Understanding the chemical complexity of the extracellular matrix (ECM) and how chemical, biological, and physical cues bring changes to the behavior of cells has remained a grand challenge. Addressing these questions requires not only achieving systematic control over the interactions between cells and the ECM but also utilizing suitable analytical...
My submission is a data dashboard that depicts global trends for new and total COVID-19 cases between Jan 01, 2020 and March 08, 2021. It contains two tabs (new and total cases) with three interactive visualizations. Two maps, an original and a log-scale-filled, show the number of new COVID-19 cases...
Since the standardization of the modern brass quintet in the middle of the twentieth century, extensive research has been dedicated to the history of the genre, ensembles which have promoted and advanced brass chamber music and the growing body of original brass quintet repertoire. Such scholarship has provided practical benefits...
Introduction: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction associated with reduced quality of life, increased rates of depression and anxiety, and high economic burden to society and the individual. Current behavioral interventions, which target well-known symptom exacerbating factors such as catastrophizing and gastrointestinal- specific anxiety, have demonstrated...
Background: Evidence supporting a bidirectional relationship between depression and recurrent cardiovascular disease (CVD) appears strong, but there remains a need to better characterize the role of depression in CVD risk and cardiovascular health (CVH) promotion, especially in the context of comorbid risk factors such as cigarette smoking. In the present...
This report shows that compensation plans have not met the needs of victims of nuclear disasters for three primary reasons: compensation plans have been devised by unelected officials and without full public knowledge or participation, governments have often capped the liability of the owners of nuclear facilities, which distorts cost-benefit...
Patients with sickle cell disease (SCD) experience lifelong struggles with both chronic and acute pain, often requiring medical intervention. Pain can be managed with medications, but dosages must balance the goal of pain mitigation against the risks of tolerance, addiction and other adverse effects. Setting appropriate dosages requires knowledge of...
Human skin oils are significant scavengers of atmospheric oxidants in occupied indoor environments. Many techniques used to study gas-phase transformations of surface films indoors have been limited to off-line bulk analysis, although more surface-selective methodologies are emerging. Here, we present a multi-prong analytical approach to characterizing skin oil ozonolysis. Skin...
The Operating System (OS) kernel is a key component of modern computing infrastructure, yet it is prone to numerous vulnerabilities, many of which cause memory corruptions that can be exploited by attackers to perform malicious activities. While various techniques have been introduced to secure the Linux kernel, it still constantly...
