Extracellular vesicles (EVs) mediate intercellular communication through transfer of RNA and protein between cells. Thus, understanding how cargo molecules are loaded and delivered by EVs is of central importance for elucidating the biological roles of EVs and developing EV-based therapeutics. While some motifs modulating the loading of biomolecular cargo into...
A vast portion of the Universe is predicted to consist of an as-of-yet undetected, non-luminous form of matter, known as dark matter. Evidence of its existence has been corroborated by various astrophysical observations at many cosmological scales, and its relative abundance has been determined. However, knowledge of its nature and...
This Handbook provides resources that help explain and contextualize the intersecting crises that destabilized Mali in 2012-2013. These crises included a rebellion by Tuareg separatists, a coup by junior officers, and violence carried out by Muslim militants. In addition to an overview of the crisis, the Handbook contains historical timelines,...
This is the introductory chapter of my forthcoming book with the same title. The three primary objectives of this book are to reveal the paradigm shift of the contemporary international judiciary, conceptualize how new–style international courts (ICs) contribute to international politics, and normalize our understanding foremost as courts, and second...
In this paper, I present two distinct approaches to migrant entrepreneurship. I conducted an ethnography of two Ghanaian migrant businesses, one of which draws on the Ghanaian community, and the other which distances itself from it. I show that our current understanding of social capital romanticises the notion of community,...
The causes and consequences of geophagy, the craving and consumption of earth, remain enigmatic, despite its recognition as a behavior with public health implications. Iron deficiency has been proposed as both a cause and consequence of geophagy, but methodological limitations have precluded a decisive investigation into this relationship. Here we...
The leptonic and inclusive hadronic decay branching fractions of the W boson are studied using 35.9 $fb^{-1}$ of proton-proton collision data collected at $\sqrt{s}=13~TeV$ during the 2016 run of the CMS experiment. Events characterized by the production of pairs of W bosons from \ttbar and \tW processes are selected. Multiple...
The need for readily synthesized scaffold architectures to build monodisperse, high molar mass mobility modifiers or "drag-tags" in end-labeled free solution electrophoresis (ELFSE) led to the development of a novel class of multivalent molecular tools. Poly-N-substituted glycines (peptoids) were created with evenly spaced amino groups as branching points along the...
Virtual machine based distributed computing greatly simplifies and enhances adaptive/autonomic computing by lowering the level of abstraction, benefiting both resource providers and users. We are developing Virtuoso, a middleware system for virtual machine shared-resource computing (e.g. grids) that provides numerous advantages and overcomes many obstacles a user faces in using...
A comprehension of the complex dynamics of gaseous combustion requires an understanding of the underlying fundamentals. In this dissertation, I examine planar diffusion flames from both an experimental and numerical perspective.
In the first part of this thesis, I study the extinction of unstrained, planar counter-diffusion flames. The theoretical model...